Delayed hemolytic transfusion reactions.
نویسنده
چکیده
Delayed hemolytic transfusion reactions continue to occur in spite of the use of all of the currently available techniques of antibody detection. Both low titers of the antibodies and dosage effects appear to contribute to the failure of detection. A rapid anamnestic response can occur with transfusion of the appropriate antigen. The clinical as well as the laboratory presentation of delayed hemolysis may vary from case to case and thus confuse the true nature of the reaction. The Kidd antibodies are, as a group, more frequently reported in delayed reactions than are any other antibodies.
منابع مشابه
Case reports: delayed hemolytic transfusion reaction in sickle cell disease.
This article reports the details of delayed hemolytic transfusion reactions in four patients with sickle cell disease. These cases demonstrate the characteristics of the reactions, the significant risks involved, and the principles useful in diagnosis and treatment. Patients with sickle cell disease are at particular risk for delayed hemolytic transfusion reactions because they may be transfuse...
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When a reaction occurs during or after the transfusion of a blood product, those involved in the care of that patient tend to think first of an immunological evenł. l However, many transfusion reactions may not be immunologically mediated. The differential diagnosis of a transfusion reaction should include the many nonimmune conditions that can lead to the destruction of either donor or recipie...
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BACKGROUND Transfusion is a cornerstone of the management of sickle cell disease but carries a high risk of hemolytic transfusion reaction, probably because of differences in erythrocyte antigens between blood donors of European descent and patients of African descent. Patients may experience hemolytic transfusion reactions that are delayed by from a few days to two weeks and manifest as acute ...
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متن کاملRed blood cell alloimmunization in sickle cell disease: pathophysiology, risk factors, and transfusion management.
Red blood cell transfusions have reduced morbidity and mortality for patients with sickle cell disease. Transfusions can lead to erythrocyte alloimmunization, however, with serious complications for the patient including life-threatening delayed hemolytic transfusion reactions and difficulty in finding compatible units, which can cause transfusion delays. In this review, we discuss the risk fac...
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ورودعنوان ژورنال:
- Annals of clinical laboratory science
دوره 3 1 شماره
صفحات -
تاریخ انتشار 1973